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De-risk your drug development pipeline in the early stages with well-defined MULTISCREEN™ GPCR Liability Panels

○ 50-GPCRs with well-defined CNS, cardiac, pulmonary and GI concerns

 

○ Designed to streamline the process of in vitro safety pharmacology profiling and waste less time investigating suboptimal compounds

 

○ Address potential toxicity early to advance the best drug candidate to market as quickly as possible

 

○ Available in endogenous cAMP or Calcium read-out

 

○ Publication-quality data in agonist and antagonist modes,

shared with control and raw data

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MULTISCREEN™ 50-GPCR+ Off-Target Safety Panel

MULTISCREEN 50-GPCR+ Safety Panel Table-1
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Assay Performance

5-HT2B Calcium Assay

Catalog C1325-1

5-HT2B Calcium Assay

Alpha2A Calcium Assay

Catalog C1434-1a

Alpha2A Calcium Assay

What do our customers say?

"Multispan performs GPCR screening for us on a battery of 32 typical targets and off-target GPCRs in drug discovery. What is most impressive about their work product is that they determine functionality (agonist, partial agonist and antagonist) and potency from dose-response curves using multiplexing of assays. After comparison between vendors, we found Multispan to be the least expensive option and to provide the greatest value for the funds we have available. The post-assay customer interface is excellent in that they answer questions and provide relevant commentary as needed."
 
---Allen Reitz, Ph.D.
Chief Executive Officer, Fox Chase Therapeutics Discovery, Inc.
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info@multispaninc.com

 

www.multispaninc.com

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Multispan, Inc., 26219 Eden Landing Road, Hayward, CA 94545, United States, 510-887-0817

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