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title: MULTISCREEN™ HTS β-Arrestin Assay for Native GPCRs
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| View in browser Follow us on Linkedin to receive more updates! Pioneering Next-Gen GPCR Assays ○ TRUE PHARMACOLOGY Enables the study of untagged GPCRs in their native form to mirror true physiological interactions   ○ RELEVANCE IN DATA Allows for the assay of endogenously expressed GPCRs to reflect in-vivo conditions   ○ MAXIMUM VERSATILITY Characterizes orphan GPCRs with “All-Assays-in-One-Cell-Line” broadening potential targets and streamlining drug development Explore More! MULTISCREEN™ GPCR β-Arrestin Assay Examples HEK293T AT1 Stable Cell Line Transiently Converted with β-Arrestin1 and β-Arrestin2 BacMam Sensors Learn More MULTISCREEN™ HTS β-Arrestin Assay Technology for Native GPCRs in Recombinant or Primary Cells Unique Membrane Sensor Eliminated GPCR Tagging Learn More What Do Our Customers Say? “Over the past two years I worked with Multispan on the discovery and optimization of partial agonist ligands for a Gi/o coupled GPCR. Multispan supported the in vitro effort that enabled the compound optimization by implementing and running radiolabel binding assays to evaluate the affinity of ligands, cAMP assays in agonist and antagonist modes to evaluate functional activity, GTPgS assays to accurately measure the efficacy of ligands on the receptor, ARRB-2 assays to evaluate the arresting signaling pathway and receptor internalization assays to evaluate functional activity. The work performed by Multispan was professional with good reproducibility from week-to-week, quick turnaround and cost effective. The Multispan team is easy to work with and when the assays deviated from the norm they were quick to repeat the data and address problems."   Julio Medina, Ph.D. R2M Pharma Inc. C.E.O. View Testimonials   info@multispaninc.com   www.multispaninc.com Multispan, Inc., 26219 Eden Landing Road, Hayward, CA 94545, United States, 510-887-0817 Unsubscribe Manage preferences |
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