Eliminate the Translational Gap with the MULTISCREEN™ HTS-Ready Ortholog GPCR Panel

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Characterize Effects of Drug Candidates on GPCRs from Multiple Model Organisms with MULTISCREEN^TM HTS Cell Assays

• Predict compound activity across species early in the screening process

• Reduce the animal model translational gap

• Develop and test in orthologous GPCR assays from

mouse, rat, dog, rhesus, cynomolgus, rabbit, ferret, and guinea pig

• In parallel to human GPCRs in parental cell lines and expression vectors

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EXAMPLE: MULTISCREEN™ Mouse B2 Calcium and cAMP Assays

Mouse B2 Calcium Data

Mouse B2 cAMP Data

Incorporate Ortholog Screens into Lead Generation Programs to Reduce Translational Uncertainty

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MULTISCREEN™ Ortholog GPCRs

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Customize a panel for your research program's specific needs! Inquire: info@multispaninc.com

What do our customers say?

"I have worked with Multispan, Inc, on multiple drug development programs, utilizing their GPCR platforms over past 5 years. Their team are true experts in the field, where their data is always highly robust and reproducible, and the team is highly responsive and easy to work with. The team at Multispan are true leaders in the field of GPCR drug discovery."

Brian Layden, MD, Ph.D.

Associate Professor of Medicine, Chief of Division of Endocrinology, Diabetes and Metabolism, University of Illinois at Chicago

info@multispaninc.com

www.multispaninc.com