β-Arrestin Translocation Detection For Native GPCRs!

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Free Your GPCR from Tagging Bias and Enable

"All Assays in One Cell Line"

MULTISCREEN™ β-Arrestin Sensor - The Next Generation!

• Study GPCRs in native form in ONE single cell line for all assays:

receptor activation, trafficking, and signaling

• No-wash homogeneous assay in 96- or 384-well microplates

• Easily capture real-time signaling kinetics

• Available as assay kits and custom cell lines

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"All Assays in One Cell Line" HTS-Ready

MULTISCREEN™ AT1 Stable Cell Line

Arrestin Assay

MULTISCREEN™β-Arrestin BacMam Assay Kit

Calcium Assay

MULTISCREEN™ Calcium 1.0 No Wash Assay Kit

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What do our customers say?

“Over the past two years I worked with Multispan on the discovery and optimization of partial agonist ligands for a Gi/o coupled GPCR. Multispan supported the in vitro effort that enabled the compound optimization by implementing and running radiolabel binding assays to evaluate the affinity of ligands, cAMP assays in agonist and antagonist modes to evaluate functional activity, GTPgS assays to accurately measure the efficacy of ligands on the receptor, ARRB-2 assays to evaluate the arresting signaling pathway and receptor internalization assays to evaluate functional activity. The work performed by Multispan was professional with good reproducibility from week-to-week, quick turnaround and cost effective. The Multispan team is easy to work with and when the assays deviated from the norm they were quick to repeat the data and address problems."

Julio Medina, Ph.D.

R2M Pharma Inc.

C.E.O.

info@multispaninc.com

www.multispaninc.com