Advance Target Discovery with MULTISCREEN™ 231-GPCR Panel

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Improve specificity and safety of off-target effects

for lead candidates in early-stage discovery
with MULTISCREEN™ GPCR panels

• 231 unique GPCRs available!

• Cell-based assays to directly capture biologically relevant function of compounds

in agonist and antagonist modes

• Publication-quality data, shared with control and raw data

• Discover or repurpose compounds and identify potential toxicity

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Custom assay panels for your specific needs are available!

Inquire: info@multispaninc.com

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Rapid Turnaround

• 231-GPCR cell-based functional assay panel: 1-month

• 32-GPCR safety functional assay panel: 2 weeks

• Weekly SAR lead optimization primary assays: 1 day!

MULTISCREEN™ 231-GPCR

Cell-Based Functional Assay Panel

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What do our customers say?

"Multispan provided us with target engagement data for a novel target for a rare genetic neurological disease. I collaborated with scientists at Multispan to optimize the conditions for a Gi/o coupled GPCR to generate robust assay data for both AI-generated focused library screening and dose-response potency data. In conjunction with our in-house brain organoid disease model data, we successfully identified candidates for lead optimization that engage the target and rescue the disease phenotype. Multispan scientists were proactive to suggest approaches to optimize assay quality and conducted additional experiments on several occasions to ensure high assay quality."

---Jon Hawkinson, Ph.D.

Former Vice President, Drug Discovery, Vyant Bio Adjunct Professor, Department of Medicinal Chemistry, University of Minnesota

info@multispaninc.com

www.multispaninc.com